Seroprevalence of Trypanosoma cruzi infection in blood donors in the extreme South of Brazil.

BACKGROUND: We aimed to evaluate the seroprevalence of Chagas disease among blood donors in southern Rio Grande do Sul, Brazil. METHODS: The study was conducted from 2010 to 2019 based on data registered by the Hemocentro Regional de Pelotas, Rio Grande do Sul. RESULTS: There were 106,320 blood donations, and the discard rate of blood bags, either due to positive reactions to anti-T. cruzi antibodies or inconclusive results was 0.27% (283 bags). CONCLUSIONS: The usage of methods that enable the safe identification of donors with positive serology for Chagas disease is fundamental to ensure transfusional safety.

Seroprevalence of Trypanosoma cruzi infection in blood donors in the extreme South of Brazil

ABSTRACT Background: We aimed to evaluate the seroprevalence of Chagas disease among blood donors in southern Rio Grande do Sul, Brazil. Methods: The study was conducted from 2010 to 2019 based on data registered by the Hemocentro Regional de Pelotas, Rio Grande do Sul. Results: There were 106,320 blood donations, and the discard rate of blood bags, either due to positive reactions to anti-T. cruzi antibodies or inconclusive results was 0.27% (283 bags). Conclusions: The usage of methods that enable the safe identification of donors with positive serology for Chagas disease is fundamental to ensure transfusional safety.

Current situation of Chagas disease vectors (Hemiptera, Reduviidae) in Southern Rio Grande do Sul State, Brazil.

Chagas disease (CD) has been considered endemic in the South of Rio Grande do Sul (RS) State, Brazil. This study aimed at evaluating the occurrence of Trypanosoma cruzi vectors based on the main species captured in Southern Rio Grande do Sul State from 2008 to 2019. The study area comprised counties that belong to the 3rd Regional Health Coordination (RHC) and to the 7th RHC, whose headquarters are in Pelotas and Bage, respectively. The study was based on secondary data provided by the partnership between the Federal University of Pelotas, Rio Grande do Sul State (UFPel-RS) and the State Health Surveillance Center in RS (SCHS-RS). One thousand and four hundred triatomines were captured in the area supervised by the 3rd RHC, mainly in Cangucu (37.7%), Piratini (22.4%) and Pinheiro Machado (15.1%), while, in the area supervised by the 7th RHC, the largest number of triatomines was captured in Lavras do Sul (64.15%). In both areas, Triatoma rubrovaria (90.6%) and Panstrongylus tupynambai (7.4%) were the most common species. Most were captured inside households but T. cruzi-positive insects were not found in the period under study. The results of this study show that, in Southern Rio Grande do Sul State, there is still a high rate of triatomine household invasion and dispersal, mainly by T. rubrovaria. Thus, the entomological surveillance should be maintained with the participation of the population and further studies should be deepened in the area.

Seroprevalence of anti-TRYPANOSOMA CRUZI and anti-TOXOPLASMA GONDII antibodies in possible and potential organ donors in the south of Rio Grande do Sul state, Brazil

Serological profiles are important in cases of solid organ donation where serological findings, such as antibodies against Trypanosoma cruzi and toxoplasmosis, may interfere in organ donation by increasing morbidity and mortality. This study aimed to outline seroprevalence of anti-Trypanosoma cruzi and anti-Toxoplasma gondii antibodies in possible and potential organ donors in the south of Rio Grande do Sul (RS) State, Brazil. A cross-sectional quantitative and retrospective epidemiological study was carried out, based on secondary data. Data on serology were extracted from medical records found in the Sistema de Gestão Hospitalar (SIGH), a hospital management system used by a university hospital in the south of RS, Brazil. Sociodemographic variables, such as age, sex and race, as well as clinical variables, such as titration of IgM and IgG anti-T. cruzi and anti­T. gondii antibodies, were analyzed. Medical records were found to be poorly filled in, since 67.6% (506 records) could not be used due to lack of information. Seroprevalence of T. cruzi was 6.8% (5 cases), mostly in white males. Regarding seroprevalence of T. gondii, 76.2% (64 donors) were serologicaly positive, 10.9% of which were IgM positive. This is the first study on anti-T. cruzi and anti-T. gondii antibodies in organ donors in RS, Brazil and should be furthered since there may be consequences regarding organ uptake and donation.

Health education in chagas disease control: making an educational video

Several studies have shown that the population has relatively little information regarding Chagas disease (CD) and its vectors; however, this knowledge is relevant because community participation is vital for success in disease control actions. For this reason, and due to the lack of audiovisual material on this subject in the country, this study focused on making an educational documentary on CD and its vectors, which could be available to the population for free. The video preparation was divided into three phases: Pre-production, Production and Post-production. The site chosen for shooting was northwestern Rio Grande do Sul State due to the Triatoma infestans vector persistence in recent decades in that area. A documentary was obtained which addresses relevant CD aspects, such as its history, transmission, major vectors and biology, phases of the disease and, in particular, how to inspect the intra-domiciliary and peri-domiciliary areas in search of triatomine bugs or "kissing bugs". The use of videos as an educational tool helps broadcast information; therefore, this documentary is a public use tool, which aims to promote the control and prophylaxis of CD and its vectors.

Trichomonas vaginalis / awareness of trichomoniasis in women attended by the health service of Bagé, RS, Brazil

This study aimed to measure the level of awareness of Trichomonas vaginalis / trichomoniasis and other sexually transmitted diseases (STDs), in 300 women from 19 municipalities in the southwest region of Rio Grande do Sul, Brazil, who sought the gynecology sector of the Basic Healthcare Centers in the Municipality of Bagé from January to June 2013. The data were collected through a semi-structured questionnaire, and the results were tabulated and organized using Excel® 2010 software. Only 5.7% of the participants said they were aware of T. vaginalis / trichomoniasis and had a little information on HIV and Aids in reference to other STDs. Schooling alone was significant (p = 0.0135), as women who had a high school diploma or higher education were 6.6 times more likely to be aware of T. vaginalis. There is, therefore, a need to devise better educational campaigns, addressing this and other STDs, such as trichomoniasis, given the lack of knowledge about this parasite, its high frequency and possible escalation.

Vídeo educativo e calendário ilustrativo: instrumento para controle da doença de chagas e seus vetores no Rio Grande do Sul, 2017 / Educational video and illustrative calendar: instrument to control of chagas disease and its vectors in Rio Grande do Sul, 2017

Esse é um estudo do tipo desenvolvimento de tecnologia educativa digital, firmada com a colaboração entre pesquisadores da Universidade Federal de Pelotas (UFPel) com o Centro Estadual de Vigilância em Saúde (CEVS) e o Telessaúde-Universidade Federal do Rio Grande do Sul (UFRGS) para construção de um documentário educativo sobre a Doença de Chagas e seus vetores. (AU)